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10.1038/s41392-022-01182-w Signal Transduct Target Ther

The most common approach is one dose in the morning (following the fasted protocol) and a second dose in the late afternoon or evening, again making sure it's on an empty stomach (at least 2-3 hours after your last meal)

The big question is whether triple agonism can improve both glucose and weight strongly enough while preserving tolerability

169 It has been demonstrated that the expression of human Z AAT protein in mouse liver leads to elevated oxidative stress and lowered antioxidant protection