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doi: 10.1002/btm2.10613 75 CaoSSKaufmanRJ
Who should not take GLP-1s GLP-1s in all forms are unsuitable for people who: are pregnant or breastfeeding do not meet the eligibility criteria have a family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN2) Medical Perspective Patients with needle phobia, a preference for pill-based routines, or good adherence to oral administration guidelines may be better suited to oral GLP-1 formulations like semaglutide (Rybelsus, Wegovy), which can enhance treatment acceptance and potentially offer strong glycemic or weight control
racemization during synthesis or storage reduces potency substantially and is not detectable by standard reverse-phase HPLC (requires chiral HPLC)
doi: 10.1111/head.13214 44
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