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These include, but are not limited to, genetic predisposition, neuroinflammation, head trauma, untreated hypertension, diabetes, Parkinsons disease, HIV infection and normal aging

Healthcare providers often need to reduce the doses of these concurrent antidiabetic medications when starting semaglutide therapy, with subsequent adjustments based on glucose monitoring results and clinical response

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For example, a study of attention to task found that MAOA variants did not play a role.[ref] The MAOA and MAOB genes are located on the X chromosome, so men only have one copy of the gene