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The Clinical Evidence STEP 1 [1] (N=1,961, NEJM 2021, DOI: 10.1056/NEJMoa2032183): 14.9% mean weight loss over 68 weeks

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These tests can measure the number of red blood cells, hemoglobin levels, and iron stores

Male C57BL/6, NCG mice and Glud1 ( Gdh1 ) fl/fl mice (T018611) (68 weeks old) were purchased from GemPharmatech and were maintained under specific-pathogen-free conditions