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Many users report reduced appetite and weight loss, while others experience nausea or gastrointestinal discomfort, especially during early dose increases

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In clinical trials, GLP-1 medicines generally improve depression and anxiety measures

First, the literature search was restricted to English-language articles from PubMed, Europe PMC, Cochrane Library, and ClinicalTrials.gov, which, although they constitute the most comprehensive biomedical database regarding the subject of the review, may not have captured all relevant studies indexed in other sources, such as Scopus or Web of Science