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Pulsatile growth hormone exposure produces distinct intracellular outcomes compared with continuous hormone presence

Taken together, these results suggest that at least a proportion of the protection against diet-induced obesity (DIO) observed in global Gipr KO mice is attributable to loss of the population of Gipr -expressing GABAergic neurones located in the AP

Recent advances in understanding NRF2 as a druggable target: development of pro-electrophilic and non-covalent NRF2 activators to overcome systemic side effects of electrophilic drugs like dimethyl fumarate