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Several observational studies have suggested that people with type 2 diabetes face a higher risk of developing Parkinsons disease

the 2.4 mg dose produced 16.9%, only 3.7% more despite more than doubling the dose and significantly increasing GI side effects (Wilding et al., NEJM 2021)

Riccabona M, Darge K, Lobo M, Ording-Muller L, Augdal TA, Avni FE, Blickman J, Damasio BM, Ntoulia A, Papadopoulou F, Vivier P, Willi U (2015) ESPR Uroradiology Taskforceimaging recommendations in paediatric uroradiology, part VIII: retrograde urethrography, imaging disorder of sexual development and imaging childhood testicular torsion