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BRG1 and BRM SWI/SNF ATPases redundantly maintain cardiomyocyte homeostasis by regulating cardiomyocyte mitophagy and mitochondrial dynamics in vivo

Typical Clinical Ranges Loading Phase: 25 mg per week (subcutaneous injection) for 46 weeks Maintenance Phase: 2 mg every 12 weeks after the loading period Key Considerations Personalization: Dosage should be adjusted based on individual symptoms, sensitivities, and treatment response

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If gastrointestinal symptoms persist beyond the adjustment period, your provider modifies the titration timeline or adds supportive care