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When Side Effects Push Users Away Additionally, people who had previously used gastrointestinal medicationswhich may indicate they are more vulnerable to the common adverse gastrointestinal side-effects reported by GLP1-RA users, such as nausea, vomiting, diarrheawere 9% more likely to discontinue semaglutide within the first year

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Cold or room-temperature foods are often better tolerated than hot meals when nausea is present

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