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There are four major dopaminergic pathways, the mesolimbic and the mesocortical (important for reward-related cognition and executive functions [212]), the nigrostriatal (known for its role in motor function [213]) and the tuberoinfundibular pathway (for the regulation of prolactin secretion [214])

Consistent with the glycemic control achieved and maintained with persistence with semaglutide, these findings emphasize the durability of treatment efficacy of semaglutide