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Compare that to direct hormone replacement, which tops off levels from the outside and can sometimes suppress the glands own output over time

This characteristic can be beneficial in studies focused on stress hormone balance and its implications for recovery and body composition

During MRI, the patient must lie perfectly still in an enclosed tube, which can become very uncomfortable

After cleavage with His-TEV to remove the His-MBP tag, the eluted fraction (SNX1-His-SUMO-SNX2a) was further loaded onto a Ni-NTA column and washed with buffer containing 20 mM HEPES (pH 7.4), 200 mM NaCl, and 40 mM imidazole to remove unbound samples