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Activity-based protein profiling, coupled with functional assays, identified the glutathione peroxidase GPX4 as a target

In humans and rodents, GIP infusion results in decreased levels of cross-linked C-terminal telopeptide of type I collagen (CTX-1) and increased levels of procollagen type I N-terminal propeptide (P1NP), regardless of whether blood glucose levels are normal or elevated [50,51,52]

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