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Those who continued taking semaglutide lost an additional 7.9% body weight, resulting in a total weight loss of 17.4% over the entire trial

Results: Both groups lost weight (3.681.37 kg placebo

A few highlights: Accelerated eGFR decline during the year preceding a heart failure event Slower decline afterward but still exacerbated A parallel between eGFR slope and NYHA class, suggesting the kidney may be signaling congestion early These findings call for a shift in practice: instead of relying on static eGFR thresholds, tracking its trajectory over time could help us identify at-risk patients sooner and intervene before hospitalization

This information is especially pertinent for individuals pursuing loss of mass, contemplating the long-term consequences of their treatment choices